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1.11.0 • Published 1 week agoCLI

seqera

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BUSL-1.1
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1.11.0
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Co-Scientist CLI

AI-powered assistant for bioinformatics workflows and Seqera Platform.

Get started

  1. Install the Co-Scientist CLI:

    npm install -g seqera

    See Installation for a comprehensive installation guide.

  2. Log in to your Seqera account:

    seqera login

    See Authentication for a comprehensive authentication guide.

  3. Start Co-Scientist:

    seqera ai
  4. Run your first prompt:

    List my recent workflows

    See Use cases for a comprehensive list of use cases.

Use cases

Co-Scientist is an intelligent command-line assistant that helps you build, run, and manage bioinformatics workflows. The following sections describe several common use cases.

Work with Nextflow

Co-Scientist helps you develop, debug, and understand Nextflow pipelines with AI-powered analysis and code generation.

Working with Nextflow

Understand your pipeline structure:

> Show me the structure of main.nf
> What processes are defined in this pipeline?

Generate a nextflow.config file:

> Generate a nextflow.config for my pipeline

Debug your pipeline:

> Why is my pipeline failing?
> Run nextflow lint on my pipeline

Generate a schema (nextflow_schema.json) file:

> Generate a nextflow_schema.json for my pipeline

Convert scripts to Nextflow:

> Convert my Python script to a Nextflow process
Build containers with Wave

Co-Scientist can create containerized environments using Wave, without requiring you to write Dockerfiles.

Building containers with Wave

Create a container with conda packages:

> Create a container with samtools and bwa from bioconda

Create a container with pip packages:

> Build a container with pandas, numpy, and scikit-learn

Get a container for a specific tool:

> I need a container with FastQC version 0.12.1

Note: The assistant will generate a Wave container URL that you can use directly in your Nextflow pipelines or pull with Docker.

Customize your session

Customize your session with command-line options.

Customize your session

Start in a specific directory:

seqera ai -w /path/to/project

Set approval mode for local commands:

seqera ai -a full
Exit the assistant

End your Co-Scientist session when done.

Exit the assistant

To end your session:

  • Type /exit or /quit
  • Press Ctrl+C

Note: Your conversation history is preserved for the session but not stored permanently.

Use slash commands

Co-Scientist includes built-in slash commands for common workflows.

Use slash commands

Type / to see all available commands:

Command Description
/help (or ?) Show available commands
/exit (/quit, /q) Exit the application
/clear Clear conversation history
/thinking Toggle thinking display
/scroll Toggle auto-scroll
/org Show current organization
/session Show current session ID
/sessions Browse and switch sessions
/lsp Show LSP server status
/status Show system status (includes composer mode)
/credits Show credit balance and usage
/approval [mode] Show or set approval mode (always/default/suggest)
/update Check CLI updates and next steps
/feedback Open feedback form
/help-community Open community help
/stickers Get Seqera stickers
Work with data

Co-Scientist helps you manage data through Platform data links and access reference datasets.

Working with data

Browse data links:

> List my data links
> Show me the contents of my S3 data link

Download and upload files:

> Generate a download URL for results/final_report.html
> Upload my local results to the data link

Access reference data:

> Find the human reference genome GRCh38
> Search for RNA-Seq test data
Work with local files

Co-Scientist can interact with files in your current working directory.

Work with local files

Start the assistant from your project folder:

cd /path/to/your/project
seqera ai

Then, ask the assistant to help with local tasks:

> Show me the structure of main.nf
> Add a new process to handle quality control

Note: Local file operations are controlled by approval modes. By default, the assistant will ask for your approval before making changes outside your working directory or running potentially dangerous commands.

Work with nf-core modules

Co-Scientist provides access to over 1,000 nf-core modules for common bioinformatics tasks.

Working with nf-core modules

Search for modules:

> Find nf-core modules for sequence alignment
> What modules are available for variant calling?

Get module details:

> Show me how to use the nf-core/bwa/mem module

Run a module:

> Run FastQC on my FASTQ files

Note: The assistant can generate the exact Nextflow command with proper parameters for your data.

Work with Seqera Platform

Use Seqera Platform capabilities to run and manage workflows at scale with AI assistance.

Working with Seqera Platform

List your workflows:

> List my recent workflows

Launch a pipeline:

> Launch the nf-core/rnaseq pipeline with the test profile

Debug failed runs:

> Why did my last workflow fail?
> Get the logs for the failed task in my last run

Learn more

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